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Explain the relationship between the terms virus particle,virion,and virus genome.

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A virus particle is a broad term used to...

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In E.coli,the adenine in the sequence GATC is methylated by the Dam enzyme.In the same cells a restriction endonuclease recognizes and cleaves dsDNA with GATC on either strand.Why does E.coli have these two enzymes?


A) The enzymes cut the E.coli genome into pieces that bind to viral particles and inhibit viral replication.
B) The enzymes increase the rate of mutation and genome rearrangement,thus increasing the likelihood that E.coli cells will mutate and become resistant to viral infection.
C) The enzymes encourage lysogeny because the cleavage sites are recognized by viral integrases.
D) The enzymes protect E.coli from infection by preferentially degrading viral or other exogenous DNA that is not methylated.

E) C) and D)
F) A) and D)

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How do bacteriophage influence bacterial evolution?


A) Bacteriophage cause cleavage and rearrangement of bacterial genomes,thus accelerating bacterial evolution.
B) Bacteriophage lyse mutated bacterial cells,thus preventing them from replicating and passing on their genetic information.
C) Bacteriophage transfer genetic information between bacterial cells through transduction,thus increasing the genetic diversity of bacterial populations.
D) Bacteriophage decrease the size of bacterial populations and thus decreasing genetic diversity and slowing down bacterial evolution.

E) B) and D)
F) All of the above

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When a virus enters a host cell in which it can replicate,the process is called a(n)


A) insertion.
B) infection.
C) prophage.
D) excision.

E) A) and D)
F) All of the above

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Relate the structure of bacteriophages and animal viruses to the structure of their respective host cells and the steps of the viral life cycle.

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The T4 phage has a very complex structur...

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Why do scientists believe that most of the unexplored genetic diversity on Earth resides in viral genomes? Why is this genetic diversity important to human society?

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First,there are ten times as many virus ...

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Influenza is an acute human viral disease that causes brief cellular damage followed by healing and complete clearing of the virus from the body. Hepatitis C is a chronic viral disease that causes slow destruction of tissue and persistent virions that are not completely cleared.Which of these diseases is more likely to be caused by lytic virus and which is caused by a lysogenic virus?

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Persistent viral infections occur when t...

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A lytic infection results in death of the host cell.

A) True
B) False

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The primer for retrovirus reverse transcription is a specific


A) tRNA encoded by the cell.
B) tRNA encoded by the virus.
C) nuclear tRNA.
D) nuclear tDNA.

E) A) and D)
F) All of the above

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There is at least one known virus whose genome is actually larger than a cellular genome.

A) True
B) False

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Which of the following enzymes would you expect to find in the virion of a retrovirus,but NOT in a bacteriophage?


A) lysozyme
B) methylase
C) restriction enzymes
D) reverse transcriptase

E) A) and B)
F) B) and D)

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RNA viruses encode host restriction systems designed to destroy host DNA.

A) True
B) False

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A virus that kills its host is said to be


A) lytic or virulent.
B) temperate.
C) lysogenic.
D) virulent or lysogenic,but not temperate.

E) A) and D)
F) None of the above

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The size and shape of viral particles is largely governed by the size and packaging of the viral


A) envelope.
B) enzymes.
C) prophage.
D) genome.

E) A) and B)
F) B) and C)

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Compare and contrast a typical bacterial growth curve and a viral one-step growth curve.Explain why the growth curves are different based on bacterial and viral replication.

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The time where replicated viruses remain...

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The latent phase in the viral growth curve and the lag phase of the bacterial growth curve are equivalent and represent the time it takes for the virus or bacterium to adapt to the culture conditions and begin growing.

A) True
B) False

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Viral replication is


A) independent of the host cell's DNA but dependent on the host cell's enzymes and metabolism.
B) independent of both the host cell's DNA and the host cell's enzymes and metabolism.
C) dependent on the host cell's DNA and RNA.
D) dependent on the host cell's DNA,RNA,enzymes,and metabolism.

E) B) and C)
F) A) and D)

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Viral size is generally measured in


A) micrometers.
B) picometers.
C) nanometers.
D) centimeters.

E) B) and D)
F) B) and C)

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Based on your knowledge of cellular and viral processes,which of the following would be (an) appropriate target(s) for antiviral drugs?


A) integrases
B) aminoacyl-tRNA synthetases
C) ribosomes
D) aminoacyl-tRNA synthetases and ribosomes

E) None of the above
F) All of the above

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An RNA genome itself serves as mRNA in negative-stranded RNA viruses.

A) True
B) False

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