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T lymphocytes


A) migrate from the thymus to the bone marrow where they mature.
B) which recognize "self-cells" leave the thymus and enter lymphatic vessels and organs.
C) must have the antigen presented to them by an antigen presenting cell.
D) develop into plasma cells once activated.
E) are a component of the bodies nonspecific immune defenses.

F) None of the above
G) A) and D)

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Doctors can easily examine lymph nodes to see if a patient is fighting disease because


A) many lymph nodes are superficial.
B) all lymph nodes are superficial.
C) lymph nodes become hot when fighting disease.
D) lymph nodes secrete pus when fighting an infection.
E) lymph nodes are concentrated in the abdomen.

F) A) and E)
G) D) and E)

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Which of the following is NOT true regarding B-cell receptors?


A) They bind with specific antigens.
B) They cause B cells to produce plasma cells and memory B cells when activated.
C) They may never encounter the antigen which binds to them.
D) They are identical to the antibodies produced by plasma cells which they activated.
E) They may be changed by the B cell in response to whatever pathogen is present.

F) A) and D)
G) C) and D)

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If a person has a genetic defect in the metabolic pathway which produces cytokines, then


A) macrophages will not be produced by the immune system.
B) B cells would not be activated to respond when cells presenting antigens are present.
C) helper T cells would take over the role of activating B cells.
D) the spleen would destroy all red blood cells.
E) histamine will not be produced by mast cells.

F) B) and C)
G) B) and D)

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What is the effect of T cells not undergoing apoptosis after the defeat of an infection?


A) An HIV infection may result.
B) Leukemia or lymphoma may result.
C) The future immunity is that much stronger.
D) An autoimmune disease may result.
E) An allergy may result.

F) A) and E)
G) C) and D)

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When the body responds to its own cells as foreign antigens, this results in ________.


A) allergies
B) autoimmune disease
C) passive immunity
D) anaphylactic shock
E) active immunity

F) A) and D)
G) A) and C)

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Which statement about vaccines is correct?


A) Vaccines will always cause the patient to become ill in order to build the immune system.
B) Vaccines never cause the patient to become ill in order to build the immune system.
C) Vaccines are not intended to cause the patient to become ill in order to build the immune system.
D) Vaccines need to be administered on a continuous basis in order to be effective.
E) It is only necessary to be vaccinated once in order to have immunity for your entire life.

F) B) and E)
G) All of the above

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Bacteria moved out of the lungs by cilia in the respiratory system are prevented from entering the body because the are often killed by


A) lymphocytes in the saliva.
B) filters lining the pharynx.
C) stomach acid.
D) lymph nodes at the base of the tongue.
E) mucus in the trachea.

F) B) and D)
G) D) and E)

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Figure: Figure:   -In this figure,  B  represents ____________ which is released by  A , _________. A)  histamine; mast cells B)  histamine; neutrophils C)  antibodies; mast cells D)  pathogens; bacteria E)  antibodies; B cells -In this figure, "B" represents ____________ which is released by "A", _________.


A) histamine; mast cells
B) histamine; neutrophils
C) antibodies; mast cells
D) pathogens; bacteria
E) antibodies; B cells

F) C) and D)
G) A) and D)

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During an inflammatory response, macrophages consume debris and cause the release of colony-stimulating factors which increase production of white blood cells by the bone marrow.

A) True
B) False

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Figure: Figure:   -David was in a car accident and needed a blood transfusion due to his injuries. His brother, Steve, went to the hospital hoping to donate blood to be used in the transfusion. David's blood type is type B. Steve's blood type is type AB. Which of the following statements is true regarding Steve's potential donation? A)  David can not receive Steve's blood because of the antibodies in Steve's blood. B)  David can not receive Steve's blood because of the antigens on David's blood. C)  David can not receive Steve's blood because of the antibodies in David's blood. D)  David can receive the transfusion from Steve. E)  David can receive blood from Steve as long as it is only a small amount. -David was in a car accident and needed a blood transfusion due to his injuries. His brother, Steve, went to the hospital hoping to donate blood to be used in the transfusion. David's blood type is type B. Steve's blood type is type AB. Which of the following statements is true regarding Steve's potential donation?


A) David can not receive Steve's blood because of the antibodies in Steve's blood.
B) David can not receive Steve's blood because of the antigens on David's blood.
C) David can not receive Steve's blood because of the antibodies in David's blood.
D) David can receive the transfusion from Steve.
E) David can receive blood from Steve as long as it is only a small amount.

F) None of the above
G) A) and B)

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Figure: Figure:   -The letter  A  in the figure shown here is referring to a(n)  _________. A)  sweat gland B)  oil (sebaceous)  gland C)  salivary gland D)  blood vessel E)  lymph node -The letter "A" in the figure shown here is referring to a(n) _________.


A) sweat gland
B) oil (sebaceous) gland
C) salivary gland
D) blood vessel
E) lymph node

F) A) and B)
G) A) and C)

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Which of the following is not correct in describing the spleen?


A) It contains red pulp and white pulp.
B) It is an essential organ for survival.
C) It can be involved in fighting cancer.
D) It is spongy, containing many sinuses.
E) It is easily ruptured by a severe blow or infection.

F) B) and E)
G) A) and B)

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Natural killer cells can destroy cancer cells which have lost their "self" proteins.

A) True
B) False

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Which of the following shows the function of cytotoxic T cells in correct order?


A) perforin released - cytotoxic T cell binds to virus-infected cell - granzymes delivered - apoptosis occurs in virus-infected cell
B) cytotoxic T cell binds to virus-infected cell - granzymes delivered - apoptosis occurs in virus-infected cell - perforin released
C) apoptosis occurs in virus-infected cell - perforin released - cytotoxic T cell binds to virus-infected cell - perforin released
D) cytotoxic T cell binds to virus-infected cell - perforin released - granzymes delivered - apoptosis occurs in virus-infected cell
E) granzymes delivered - perforin released - apoptosis occurs in virus-infected cell - cytotoxic T cell binds to virus-infected cell

F) A) and B)
G) A) and C)

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_________ of T lymphocytes leave the thymus.


A) 5%
B) 10%
C) 50%
D) 75%
E) 24%

F) D) and E)
G) A) and E)

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Which of the following is NOT true about passive immunity?


A) It is temporary.
B) It can be gained by infants through breast milk.
C) It is achieved through the production of antibodies by the person gaining the immunity.
D) It can be achieved through injections of antibodies or immunoglobulins.
E) It can be used to prevent an illness in someone who has been exposed to that illness.

F) A) and B)
G) B) and D)

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One way the complement system acts is by producing


A) proteins that assist neutrophils in recognizing a pathogen.
B) mast cells that attack pathogens' membranes.
C) histamines that stimulate B cell formation.
D) kinins that bind to the surface of pathogens.
E) macrophages that phagocytize bacteria.

F) A) and B)
G) B) and E)

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Figure: Figure:   -In this figure, A is acting as a(n)  ______________. A)  antigen-presenting cell B)  helper T cell C)  neutrophil D)  antibody E)  plasma cell -In this figure, A is acting as a(n) ______________.


A) antigen-presenting cell
B) helper T cell
C) neutrophil
D) antibody
E) plasma cell

F) A) and B)
G) C) and D)

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AIDS is caused by


A) the human immunodeficiency virus which destroys helper T cells.
B) the human immunodeficiency virus which stimulates apoptosis of immune system cells.
C) allergens which stimulate helper T cells to produce cytokines.
D) bacteria which destroy lymphocytes in the bone marrow.
E) the human immunodeficiency virus which destroys macrophages.

F) A) and B)
G) A) and C)

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