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The _____ enzyme is responsible for unwinding the double-helix structure of DNA during replication.


A) helicase
B) polymerase
C) ligase
D) extendase
E) windase

F) C) and D)
G) C) and E)

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Tumor suppressor genes are


A) oncogenes that code for proteins that inhibit cell division.
B) anti-oncogenes that code for proteins that inhibit cell division.
C) oncogenes that code for proteins that stimulate cell division.
D) anti-oncogenes that code for proteins that stimulate cell division.
E) transposons that can be used as cancer therapy.

F) C) and E)
G) A) and B)

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Which of the following is NOT true about cancer cells?


A) They exhibit uncontrolled growth.
B) They can form benign or malignant tumors.
C) They exhibit disorganized growth.
D) They exhibit contact inhibition.
E) They may undergo metastasis.

F) A) and B)
G) A) and C)

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Which does NOT describe a function of the DNA polymerase molecule?


A) recognize the free nucleotide that pairs with the base on the old strand of DNA
B) read the strand of old DNA and recognize the base there
C) proofread to ensure that the proper base has been incorporated
D) make the proper nucleotide to match with the base read on the old strand
E) nucleotides are joined by hydrogen bonds

F) A) and E)
G) B) and E)

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Prior to protein synthesis,the DNA


A) attracts tRNAs with appropriate amino acids.
B) serves as a template for the production of mRNA.
C) adheres to ribosomes for protein synthesis.
D) contains anticodons that become codons.
E) must first undergo replication.

F) A) and E)
G) D) and E)

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In modern biochemical genetics,the flow of inherited information is from


A) protein \rarr RNA \rarr DNA.
B) DNA \rarr RNA \rarr protein.
C) DNA \rarr protein \rarr RNA.
D) RNA \rarr DNA \rarr protein.
E) RNA \rarr protein \rarr DNA.

F) A) and B)
G) A) and C)

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Which is NOT associated with cancer?


A) It can establish new tumors distant from the site of the primary tumor.
B) It forms new blood vessels and brings nutrients and oxygen to the tumor.
C) Cancer cells can undergo cell division repeatedly and indefinitely.
D) Tumors invade surrounding tissues and are filtered by lymph nodes.
E) A malignant mass of cells is encapsulated and does not invade adjacent tissue.

F) None of the above
G) C) and E)

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Which of the following processes does NOT take place during translation?


A) attachment of a ribosome to mRNA
B) growth of a polypeptide chain
C) binding of two tRNA molecules/ribosome
D) liberation of polypeptide from ribosome
E) production of mRNA

F) None of the above
G) B) and D)

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Which of the following is NOT true about RNA?


A) RNA transfers messages from DNA to ribosomes.
B) RNA contains the sugar ribose.
C) RNA contains adenine, guanine, uracil, and cytosine.
D) RNA is single stranded.
E) RNA forms a helix.

F) A) and B)
G) C) and E)

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The individual(s) credited with the discovery of the structure of DNA is (are)


A) Alfred Hershey and Martha Chase.
B) James Watson and Francis Crick.
C) Erwin Chargaff.
D) Rosalind Franklin and Maurice Wilkins.
E) Charles Darwin and Gregor Mendel.

F) None of the above
G) A) and E)

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Which of the following is NOT true about DNA?


A) has a double helix
B) bases held together by hydrogen bonds
C) bases are complementary to each other
D) has a deoxyribose sugar
E) contains adenine, guanine, cytosine, and uracil

F) B) and C)
G) C) and D)

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Which of these is NOT a form of a point mutation?


A) nonsense mutation
B) missense mutation
C) silent mutation
D) frameshift mutation
E) UAC becomes UAU

F) B) and E)
G) C) and D)

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Which of the following is NOT true about oncogenes?


A) They are normal genes that have undergone a mutation.
B) They cause growth factors or growth factor receptors on a cell to malfunction.
C) When mutated oncogenes turn into proto-oncogenes.
D) They cause a cell to divide repeatedly.
E) They are not alien to the cell.

F) B) and C)
G) None of the above

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Which is NOT true about the genetic code?


A) It is exactly the same in all organisms.
B) It is composed of a triplet code of three bases per codon.
C) It produces 64 different possibilities of codon sequences.
D) Some amino acids are coded for by more than one codon.
E) It contains start and stop codons as instructions.

F) B) and D)
G) A) and B)

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A cell of the pancreas would specialize in producing insulin,among other functions,while a muscle cell would specialize in the production of the protein myosin,this means that


A) Pancreas and muscle cells have the genes for both insulin and myosin active.
B) The active gene in pancreas cells is the one for insulin while the muscle cells have genes for insulin and myosin.
C) Pancreas cells have a gene that would produce insulin while muscle cells have a gene that would produce myosin.
D) Neither pancreas cells nor muscle cells are specialized.
E) Only muscle cells can produce proteins.

F) C) and D)
G) C) and E)

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Which is the process that synthesizes mRNA?


A) translation
B) transcription
C) transposition
D) transformation
E) translocation

F) B) and E)
G) A) and B)

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An oncogene is


A) a viral gene with no relation to the host cells genes.
B) a mutated form of a proto-oncogene.
C) a bacterial gene that causes cancer in the host.
D) always seen in human cancer cells.
E) a gene that turns off cellular reproduction.

F) D) and E)
G) A) and C)

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The amount of adenine is always equal to the amount of ____ in DNA.


A) cytosine
B) uracil
C) guanine
D) thymine
E) ATP

F) B) and E)
G) D) and E)

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For translation to take place,which of the following would NOT be required to be present?


A) DNA
B) mRNA
C) tRNA amino acid complex
D) rRNA
E) ribosome

F) D) and E)
G) A) and E)

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Which of the classes of RNA molecules is linked with proteins in forming the large and small subunits of a cytoplasmic structure?


A) ribosomal RNA
B) transfer RNA
C) messenger RNA
D) primary mRNA transcript
E) ribozymes

F) D) and E)
G) C) and D)

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